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What Is Shaking Puppy Syndrome?


By K9Reproduction.com Editorial Updated Sep. 7, 2022

What Is Shaking Puppy Syndrome?

Shaking puppy syndrome, also known as hypomyelination, affects a young dog’s central or peripheral nervous system, causing tremors throughout the body. Myelin is the fatty protective sheath that covers nerves, facilitating the transmission of electrical impulses. When this sheath is too thin, as in hypomyelination, nerve signals are disrupted, leading to muscle malfunction and tremors.

Symptoms of Shaking Puppy Syndrome

Symptoms of shaking puppy syndrome typically begin as early as 2 weeks of age. These include:

  • Tremors: Shaking usually intensifies during activities such as eating or playing and subsides during rest.

  • Difficulty Walking: Puppies may have issues with balance and coordination.

  • Wide-Based Stance: To stabilize themselves, affected puppies may stand with their legs farther apart than normal.

  • Mentally Normal: Despite physical symptoms, puppies generally appear mentally normal.

Causes of Hypomyelination

Hypomyelination is hereditary and certain breeds are more predisposed, including:

  • Springer Spaniel

  • Australian Silky Terrier

  • Weimaraner

  • Golden Retriever

  • Catahoula Cur

  • Dalmatian

  • Chow Chow

  • Welsh Springer Spaniel

  • Vizsla

  • Samoyed

  • Bernese Mountain Dog

Male dogs are more prone to develop the syndrome than females. In Golden Retrievers, the syndrome affects the peripheral nervous system, causing symptoms without the characteristic shaking. In Springer Spaniels, the syndrome is particularly severe in males, who often do not survive past 6 months.

Diagnosing Hypomyelination

Diagnosis involves ruling out other potential issues. The veterinarian will:

  1. Physical Exam: A thorough examination to check for physical abnormalities.

  2. Neurologic Exam: To rule out spinal cord or cranial nerve damage.

  3. Blood Tests: To check for organ function and toxicities.

  4. Radiographs: Imaging to look for tumors or skeletal damage.

  5. Genetic Tests: To detect mutations responsible for hypomyelination.

  6. Advanced Imaging: CT, MRI, or myelography may be recommended to rule out other conditions.

A definitive diagnosis can only be made by examining the spinal cord post-mortem, making it a diagnosis of exclusion.

Treating Shaking Puppy Syndrome

There is no specific treatment for hypomyelination. Fortunately, most affected puppies eventually recover. Recovery timelines vary:

  • Less Severe Cases: Puppies may recover by 3-4 months of age.

  • More Severe Cases: Puppies are generally normal by 1 to 1.5 years old but may have lifelong mild hind limb tremors.

FAQs

Q: What breeds are most affected by shaking puppy syndrome?

A: Breeds such as Springer Spaniels, Weimaraners, Golden Retrievers, and others listed above are more predisposed to the syndrome.

Q: Can shaking puppy syndrome be cured?

A: There is no specific cure, but most puppies eventually recover by 1 to 1.5 years old.

Q: How is shaking puppy syndrome diagnosed?

A: Diagnosis involves ruling out other conditions through physical exams, blood tests, radiographs, genetic tests, and advanced imaging.

Q: Are male or female puppies more affected?

A: Male puppies are more prone to develop shaking puppy syndrome than females.

Q: What should I do if my puppy shows symptoms of shaking puppy syndrome?

A: Consult your veterinarian for a thorough examination and appropriate diagnostic tests to rule out other conditions.

Real-World Examples

Case Study 1: Golden Retriever Puppy

A 6-week-old Golden Retriever puppy started showing signs of uncoordinated movement and tremors. Genetic testing confirmed hypomyelination. With supportive care and monitoring, the puppy showed significant improvement by 4 months old and led a relatively normal life, though mild tremors persisted.

Case Study 2: Springer Spaniel Puppy

A 3-week-old male Springer Spaniel exhibited severe tremors and difficulty walking. Despite intensive care, the severity of the symptoms led to a poor prognosis. Unfortunately, the puppy did not survive past 6 months.

Case Study 3: Mixed Breed Puppy

A mixed breed puppy began showing mild tremors at 2 weeks old. With regular veterinary check-ups and supportive care, the puppy’s condition improved significantly by 6 months, with only occasional hind limb tremors.

For more detailed information on pet health and care, visit K9Reproduction.com.


Shaking Puppy Syndrome
Shaking Puppy Syndrome

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