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Understanding Lupoid Onychodystrophy in Dogs: A Veterinary Perspective

K9 Repro Team

Lupoid onychodystrophy, also known as symmetrical lupoid onychitis (SLO), is a rare but concerning condition affecting a dog’s toenails. This disorder typically involves all four feet and multiple nails, leading to brittle, cracked, and deformed nails that can eventually fall off, exposing the sensitive nail bed beneath. This exposure causes significant pain and potential secondary infections, making early diagnosis and treatment essential.

Lupoid onychodystrophy
Lupoid onychodystrophy

What Is Lupoid Onychodystrophy?

Lupoid onychodystrophy is characterized by the rapid onset of nail abnormalities. The affected nails become dry, brittle, and prone to crackin


g and splitting. If a nail falls off, it leaves the "quick" exposed, leading to pain and possible infection. Dogs suffering from this condition often lick their feet excessively and may have difficulty walking. Although the precise cause of SLO is not completely understood, it is believed to be an immune-mediated disease with a genetic component. It is not contagious.

Breeds and Age Affected

SLO is most commonly observed in breeds such as German Shepherds, Rottweilers, and Gordon Setters. It typically manifests in dogs between the ages of 2 and 8 years, although it can also occur in puppies and senior dogs. The condition appears to be hereditary, passed down from one or both parents.

Symptoms of Lupoid Onychodystrophy in Dogs

The initial signs of SLO often include:

  • Excessive Licking: Dogs may lick their feet and nails due to pain.

  • Limping and Lameness: Pain from the affected nails can cause limping.

  • Nail Loss: Initially, one or two nails may fall off, followed by the shedding of all nails within weeks or months.

  • Red and Swollen Toes: Secondary infections can cause redness, swelling, and discharge with an unpleasant odor.

  • Nail Abnormalities: Nails may become split, cracked, brittle, thickened, deformed, and have pus or blood beneath them.

Diagnosis of Lupoid Onychodystrophy

Veterinarians typically begin by examining the appearance of the toenails and taking the dog’s history into account. To rule out other potential causes like bacterial or yeast infections, ringworm, or cancer, additional tests may include:

  • Cultures: To identify bacteria, fungi, or ringworm.

  • X-rays: To check for bone health and cancer signs.

  • Biopsy or Fine Needle Aspirate: To examine cells from the nail bed.

A definitive diagnosis usually requires a biopsy of the nail bed, as the fallen nail itself does not provide adequate diagnostic information.

Treatment of Lupoid Onychodystrophy

Treatment for SLO aims to suppress the immune system and manage symptoms. The following medications and supplements are commonly used:

  • Fatty Acids (EPA and DHA): Found in fish oils, these are fundamental in the treatment plan.

  • Immune Suppressants: Cyclosporine and azathioprine help manage the immune response.

  • Corticosteroids: Prednisone may be used initially in severe cases but is not recommended for long-term use.

  • Pentoxifylline: Helps suppress inflammatory reactions.

  • Vitamin E and Niacinamide (Vitamin B3): Often used in combination with antibiotics like tetracycline or doxycycline.

  • Frequent Nail Trims: Essential for managing nail health.

  • Antibiotics: Used to treat secondary bacterial infections.

In severe or recurrent cases, surgical removal of the toe tip (onychectomy) might be considered, though it is typically reserved for cases with significant pain and deformity.

Management and Prognosis

The prognosis for dogs with SLO is generally good once treatment begins, though nails may remain brittle and deformed. It can take three to four months to see clinical improvement. Continuous medication and supplement adherence are crucial, and frequent nail trims every one to two weeks are recommended for life.

Maintaining clean and dry paws is important, especially after outdoor walks. Medicated wipes can help with this. Additionally, diets rich in fatty acids, such as Purina® Pro Plan® for Sensitive Skin & Stomach or Hill's® Science Diet, can be beneficial if supplements are not well-tolerated.

Conclusion

Lupoid onychodystrophy is a painful and challenging condition for dogs. Early diagnosis and a comprehensive treatment plan involving immune suppression and symptomatic management are vital for improving your dog's quality of life. Regular veterinary visits, consistent medication, and proper nail care are essential for managing this condition effectively. Always consult your veterinarian for guidance tailored to your dog’s specific needs.

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